Retinoids, derivatives of vitamin A such as retinol and tretinoin, accelerate cell turnover and boost collagen synthesis. They effectively reduce fine lines, wrinkles, and acne lesions by unclogging pores and promoting epidermal renewal. However, retinoids can cause dryness, redness, and flaking—commonly known as the retinization period—especially for first-time users or those with sensitive skin.\n\nTo minimize irritation, start with a low-concentration retinol product and apply it once or twice a week at night. Gradually increase frequency as your skin builds tolerance, up to nightly use. Always pair with a moisturizer to combat dryness, and never skip your morning sunscreen—retinoid-treated skin is more photosensitive. If severe irritation occurs, reduce usage or switch to a gentler derivative like retinaldehyde under professional guidance.